Effect of continuous blood purification for management of multiple organ failure with acute renal failure.
- Author:
Lu CHEN
1
;
Jiu-hong LI
;
Ying JIANG
;
Sheng-lang ZHU
;
Jun ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Female; Hemofiltration; methods; Humans; Male; Middle Aged; Multiple Organ Failure; etiology; therapy; Pancreatitis; complications; Renal Insufficiency; etiology; therapy; Treatment Outcome; Wounds and Injuries; complications; Young Adult
- From: Journal of Southern Medical University 2008;28(5):896-897
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of continuous blood purification (CBP) for treatment of multiple organ failure (MOF) with acute renal failure (ARF).
METHODSForty-seven patients with MOF underwent CBP for an average of 3.1-/+0.5 days averagely. Continuous veno-venous hemofiltration was performed at daytime, and the substitute fluids were infused with pre-dilution at the rate of 2000-4000 ml/h. The general conditions, clinical symptoms, and serum biochemical indexes of the patients were observed and MODS score was calculated.
RESULTSAfter CBP, the MODS score of the patients decreased significantly from 9.1-/+3.5 to 5.4-/+2.7 (P<0.01) and serum creatinine decreased from 451.3-/+134.5 to 223.7-/+100.2 micromol/L (P<0.05). Twenty-nine patients survived with the survival rate of 61.7%.
CONCLUSIONCBP is effective for treatment of MOF and may help reduce the mortality rate of MOF complicated by ARF.
