Bone damage due to juvenile rheumatoid arthritis (JRA)
- Author:
Lan Thanh Nguyen
- Publication Type:Journal Article
- Keywords:
rheumatoid arthritis
- MeSH:
Bone and Bones;
Arthritis, Rheumatoid
- From:Journal of Practical Medicine
2000;383(6):13-15
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
125 cases of JRA was diagnosed and treated in Children's Hospital I (HCM city) during Jan 1996 - Apr 1998, among them 123 were diagnosed radiographically at admission, their 18,7% had bone damages. Permanent damage of cartilage and subchondral structure or deformity of bone due to chronic synovitis were reported. The role of proinflammatory cytokin such as IL-1, TNF alpha. IL-6 and IL-8 in pathogenesis of RA and JRA has been established. Anti-inflammatory and antirheumatismal medications improved the outcomes. Radiography of bonejoint is helpful for diagnosis.
