A study of effects of pingyangmycin injection on treatment of lymphangiomas in oral, maxillofacial and cervical regions.
- Author:
Qinghong GAO
1
;
Changmei WANG
;
Yuming WEN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Antibiotics, Antineoplastic; administration & dosage; Bleomycin; administration & dosage; analogs & derivatives; Child; Child, Preschool; Dexamethasone; administration & dosage; Drug Administration Schedule; Female; Head and Neck Neoplasms; drug therapy; Humans; Infant; Injections, Intralesional; Lymphangioma; drug therapy; Male; Mouth Neoplasms; drug therapy; Tongue Neoplasms; drug therapy
- From: West China Journal of Stomatology 2002;20(3):184-186
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThe purpose of this study was to investigate the indication and therapeutic effects of Pingyangmycin injection as a primary therapy of lymphangiomas in oral, maxillofacial and cervical region.
METHODSA total of 195 patients (106 males and 89 females) with lymphangiomas in oral and maxillofacial regions were treated in the affiliated dental hospital of Sichuan University from May 1990 to December 2000. The patients' ages ranged from 0.5 to 46 years. The tongue was the most commonly involved site, followed by the cheek and the neck. The 200 lymphangiomas (5 patients had 2 lymphangiomas in different sites) underwent the therapy of Pingyangmycin, which was injected as with 1 mg/ml in saline. The total dose of Pingyangmycin ranged from 5 mg to 70 mg and 5 to 58 times, 1 time per 2-4 weeks.
RESULTSThe curative rate of cystic-type lymphangiomas was the highest. Of the 51 cystic lymphangiomas, 110 capillary lymphangiomas, 18 cavernous lymphangiomas and 21 combinations of capillary and cavenous lymphangiomas, the curative rates were respectively 100% (51), 46.36% (51), 16.16% (3) and 19.05% (4), which showed a significant therapeutic effect, respectively. And 40(78.43%), 19(17.27%), 2(11.11%) and 0(0%) of them completely disappeared. There was no serious side effect with Pingyangmycin-injection treatment, such as pulmonary fibrosis.
CONCLUSIONThe treatment of injection of Pingyangmycin is a selective primary method of lymphangiomas, which can reduce the size of lymphangiomas, and make them completely disappeared.
