Biological characteristics of the adapted rabies virus 3aG-V in Vero cell.
- Author:
Xiu-shan SHI
1
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cercopithecus aethiops; Guinea Pigs; Mice; Rabbits; Rabies; immunology; virology; Rabies virus; growth & development; immunology; pathogenicity; ultrastructure; Vero Cells; Virulence; Virus Cultivation
- From: Chinese Journal of Experimental and Clinical Virology 2004;18(4):348-350
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVETo study the biological features of the adapted rabies virus 3aG-V in Vero cell.
METHODSThe virus structure, culture condition, pathogenicity, immunocompetence, toxicity and protective efficiency were studied.
RESULTSThe rabies virus 3aG-V strain could well adapt to Vero cell, the pathogenicity was very weak and the immunogenicity was very good.
CONCLUSIONThe Vero cell-adapted rabies virus strain may possibly be used as a vaccine strain.