Progress in biosythesis of diaminopentane.
- Author:
Dongxia LI
;
Ming LI
;
Hongxin WANG
;
Shuya WANG
;
Fuping LU
- Publication Type:Journal Article
- MeSH:
Biosynthetic Pathways;
Biotechnology;
Cadaverine;
biosynthesis;
Corynebacterium glutamicum;
metabolism;
Escherichia coli;
metabolism
- From:
Chinese Journal of Biotechnology
2014;30(2):161-174
- CountryChina
- Language:Chinese
-
Abstract:
Air pollution and global warming are increasingly deteriorating. Large amounts of polyamides derived from fossil fuel sources are consumed around the world. Cadaverine is an important building monomer block of bio-based polyamides, thus biotechnological processes for these polymers possess enormous ecological and economical potential. Currently, the engineered strains for biological production of cadaverine are Corynebacterium glutamicum and Escherichia coli. We review here the latest research progress of biosynthesis of cadaverine including metabolism of cadaverine in microorganisms, key enzymes and transport proteins in cadaverine synthesis pathway, optimum pathways and cadaverine yields.
