Progress in insertion sites for foreign sequence of foot and mouth disease virus.
- Author:
Yan ZHANG
;
Yonghao HU
;
Fan YANG
;
Haixue ZHENG
- Publication Type:Journal Article
- MeSH:
Foot-and-Mouth Disease Virus;
genetics;
Genetic Engineering;
Mutagenesis, Insertional
- From:
Chinese Journal of Biotechnology
2014;30(2):175-181
- CountryChina
- Language:Chinese
-
Abstract:
With the progess in studying gene structure and function of foot and mouth disease virus (FMDV), FMDV can express exogenous genes in different sites. Through transforming and modifying FMDV can achieve different application purposes such as improving virus titer, introducing tag, improving immune responses, and reducing pathogenicity. From the perspective of FMDV receiving inserted exogenous gene, this paper mainly describes the latest relevant developments of FMDV's expression to exogenous gene.
