Advances on biological activities of coumarins.
- Author:
Shao-Yul ZHANG
1
;
Lin MENG
;
Wen-Yuan GAO
;
Nai-Ning SONG
;
Wei JIA
;
Hong-Quan DUAN
Author Information
1. Tianjin Medical University, Tianjin 300070, China. pharmgao@tju.edu.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Anti-Arrhythmia Agents;
pharmacology;
Anti-HIV Agents;
pharmacology;
Antihypertensive Agents;
pharmacology;
Antineoplastic Agents, Phytogenic;
pharmacology;
Coumarins;
isolation & purification;
pharmacology;
Humans;
Plants, Medicinal;
chemistry
- From:
China Journal of Chinese Materia Medica
2005;30(6):410-414
- CountryChina
- Language:Chinese
-
Abstract:
This paper reviewed the advances on effective constituents and biological activities of coumarins in recent ten years. Coumarins are a group of important natural compounds, and have been found to have multi-biological activities such as anti-HIV, anti-tumor, anti-hypertension, anti-arrhythmia, anti-osteoporosis, assuaging pain, preventing asthma and antisepsis. Therefore, further investigation should emphasize on improving techniques for extraction and separation, searching the effective precursory compound, and synthesizing and screening out courmarin derivatives with high activity and low toxicity.
