Quality assessment of Coptis chinensis in China.
- Author:
Guo-yue ZHONG
1
;
Xiao-ping HUANG
;
Kai-sen MA
;
Shi-jiang CHEN
;
Song-yun QIN
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; analysis; Berberine; analogs & derivatives; analysis; Berberine Alkaloids; analysis; China; Chromatography, High Pressure Liquid; Coptis; chemistry; classification; Ecosystem; Plants, Medicinal; chemistry; Quality Control; Spectrophotometry, Ultraviolet
- From: China Journal of Chinese Materia Medica 2005;30(7):495-497
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the dynamic change of the ingredients of Coptis chinensis and evaluate the quality of the crude drugs from main producing areas.
METHODThe ingredients of samples from Shizhu and Wuxi counties in Chongqing, Hongya and Dayi counties in Sichuan, Zhenping county in Shanxi, Lichuan county in Hubei were analyzed for berberine, coptisine, jatrorrhizine, palmatine and the total alkaloids by HPLC and UV methods.
RESULT AND CONCLUSIONThe contents of measured indexes were mostly highest in 5-years-old C. chinensis. Considering factors such as the yield, it is reasonable to harvest the 5-years-old C. chinensis. There are minor differences in condents of C. chinensis from different areas, all tested samples met the pharmacopoeial standards. It is concluded that the general quality of C. chinensis was good and acceptable.
