Study on the effects of cool and hot ethanol extracts from qinglongyi on the biochemical function of tumor membrane in H22 mice.
- Author:
Yu-bin JI
1
;
Chen-feng JI
;
Hong-tu MA
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antineoplastic Agents, Phytogenic; isolation & purification; pharmacology; Cell Line, Tumor; Cell Membrane; drug effects; Drugs, Chinese Herbal; isolation & purification; pharmacology; Ethanol; Hot Temperature; Juglans; chemistry; Liver Neoplasms, Experimental; metabolism; pathology; Membrane Fluidity; drug effects; Membrane Proteins; metabolism; Mice; Plants, Medicinal; chemistry
- From: China Journal of Chinese Materia Medica 2005;30(7):531-534
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effects of cool and hot ethanol extracts from Qinglongyi on tumor membrane protein content, lipid fluidity, and membrane close capability in H22 mice.
METHODThe membrane protein content, by, lipid fluidity and membrane close capability were measured by means of SDS-PAGE, skinitzky assay and Zamudio method respectively.
RESULTThe cool and hot ethanol extracts from Qinglongyi decreased the content of tumor membrane protein, the lipid fluidity and membrane close capability.
CONCLUSIONThe cool and hot ethanol extracts from Qinglongyi can change the biochemical substance and biochemical function to cause disaggregation and death of the tumor cell, which may be one of the mechanisms underlying the anti-tumor of Qinglongyi.
