Study on quality control of effective fraction in qixue bingzhi decoction.
- Author:
Zai-Fang HUANG
1
;
Lian-Jun LUAN
;
Qing SHAO
;
Yi-Yu CHENG
Author Information
- Publication Type:Journal Article
- MeSH: Benzoates; analysis; Bridged-Ring Compounds; analysis; Chromatography, High Pressure Liquid; methods; Drug Combinations; Drugs, Chinese Herbal; analysis; Flavanones; analysis; Glucosides; analysis; Hesperidin; analogs & derivatives; analysis; Ligusticum; chemistry; Monoterpenes; Paeonia; chemistry; Plants, Medicinal; chemistry; Quality Control; Reproducibility of Results
- From: China Journal of Chinese Materia Medica 2005;30(8):580-583
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop a method for quality control of effective fraction in Qi-Xue-Bing-Zhi decoction, a traditional Chinese medicine (TCM).
METHODPF samples, effective fraction from Qi-Xue-Bing-Zhi decoction, were used as example, and a HPLC assay for chemical fingerprint and quantitative analysis was established.
RESULTThe contents range of Paeoniflorin (PE), Naringin (NG) and Neohesperidin (NH) in effective fractions were changed from 12.5%-16.0%, 8.4%-12.4%, 12.8%-15.3%, and their average contents were (14.7 +/- 1.1)%, (10.6 +/- 1.2)%, (14.2 +/- 0.8)% (n = 10), respectively. The fingerprints of PF samples showed 25 common peaks, and the fingerprint similarity for PF samples were all above 99.00% by comparing with the standard chromatogram.
CONCLUSIONThe method reported could be used effectively for the quality control of effective fraction from TCM.
