Analysis on processing mechanism of calamine.
- Author:
Yi-Ming GUO
1
;
Kai-Feng YU
;
Yan-Hua LIU
;
Jing-Zhe ZHAO
;
Zi-Cheng WANG
;
Heng-Bin ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Anti-Bacterial Agents; pharmacology; Carbonates; chemistry; pharmacology; Drug Combinations; Escherichia coli; drug effects; Ferric Compounds; chemistry; pharmacology; Materia Medica; chemistry; pharmacology; Nanostructures; Nanotechnology; Particle Size; Pseudomonas aeruginosa; drug effects; Salmonella; drug effects; Staphylococcus aureus; drug effects; Technology, Pharmaceutical; methods; Tetracycline; pharmacology; Thermogravimetry; Zinc Compounds; chemistry; pharmacology; Zinc Oxide; analysis; chemistry; pharmacology
- From: China Journal of Chinese Materia Medica 2005;30(8):596-599
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study processing method and mechanism of Calamine.
METHODThermogravimetry analysis method and nano-technology were adopted to analyze and synthesize the components in Calamine, Tetracycline was took as the comparison drug to determine the antibacterial activity of Calamine and its components.
RESULTA part of zinc carbonate in Calamine was decomposed into zinc oxide when processing, and the particle size was smaller than before. The antibacterial activity of Calamine is decided by the content and particle size of zinc oxide, and has nothing with zinc carbonate. The more content and the smaller particle size of zinc oxide, the more powerful antibacterial activity of Calamine.
CONCLUSIONThe content and the particle size of zinc oxide can be the important targets in the processing of Calamine.