The normal range of amniotic fluid alpha-fetoprotein in singleton midtrimester pregnancy of Korean women.
- Author:
Jun Hyung KIM
1
;
Young JI BYUN
;
Jai Sun PARK
;
Jin Young PARK
;
Jeong In YANG
;
Haeng Soo KIM
;
Hee Suk RYU
Author Information
1. Department of Obstetrics and Gynecology, Ajou University School of medicine, Suwon, Korea. yangji@ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Amniotic fluid alpha-fetoprotein (AFAFP);
midtrimester;
normal range;
singleton pregnancy;
Korean women
- MeSH:
alpha-Fetoproteins*;
Amniocentesis;
Amniotic Fluid*;
Female;
Humans;
Pregnancy;
Pregnancy Trimester, Second*;
Pregnancy*;
Pregnant Women;
Prenatal Diagnosis;
Reference Values*;
Tertiary Care Centers
- From:Korean Journal of Obstetrics and Gynecology
2007;50(12):1679-1684
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To determine normal range of amniotic fluid alpha-fetoprotein (AFAFP) in midtrimester singleton Korean pregnant women whose pregnancy and neonatal outcomes were uneventful. METHODS: AFAFP levels were measured in midtrimester pregnancy during amniocentesis from May 1995 to September 2006 at tertiary referral center. Normal ranges were obtained from 954 singleton pregnancies in which pregnancy and neonatal outcomes were normal. RESULTS: Median values of AFAFP in midtrimester pregnancy were 15,800 ng/mL, 13,903.9 ng/mL, 11,408.7 ng/mL, 9,690.1 ng/mL, 6,923.4 ng/mL, 6,330.0 ng/mL, 5,295.3 ng/mL, 4,421.2 ng/mL, 3,162.5 ng/mL at 16 week, 17 week, 18 week, 19 week, 20 week, 21 week, 22 week, 23 week, and 24 week. CONCLUSION: The normal range of AFAFP level in each gestational week in Korean women could be a good reference for prenatal diagnosis of various disorders.
