The morphological and immunological characteristics of less-differentiated acute myeloid leukemic cells.
- Author:
Yi-Yan LAI
1
;
Huo TAN
;
Xu YE
;
Xu-Hong ZHOU
;
Ying FENG
;
Lin-Juan ZENG
Author Information
1. Department of Hematology, The Second Affiliated Hospital of Guangzhou Medical College, Guangzhou 510260, China. cq2@21cn.com
- Publication Type:Case Reports
- MeSH:
Cell Differentiation;
Female;
Humans;
Leukemia, Myeloid, Acute;
classification;
immunology;
pathology;
Middle Aged
- From:
Journal of Experimental Hematology
2003;11(4):429-431
- CountryChina
- Language:Chinese
-
Abstract:
The aim was to study the morphological, histochemical and immunological characteristics of less-differentiated acute myeloid leukemic cells, and their diagnostic significance. Wright-Giemsa and histochemical staining were used to stain bone marrow smears from 2 case of AML-Mo. Immunological phenotypes were determined with flow cytometry. The results showed that myeloperoxidase stainings of both cases were negative, PAS was positive with fine particles, CD33/CD13 were positive, CD2/CD3/CD10/CD19/CD22 were negative. It is concluded that morphology, histochemistry and immunological phenotype on bone marrow smears are the main diagnostic basis for AML-Mo. The use of multiple monoclonal antibodies for staining may improve the accuracy.
