The effect of antioxidant on optimation of blood preservation.
- Author:
Jing-Han LIU
1
;
Wei HAN
;
Feng-Lei LAI
;
Yang YU
;
Rui LI
;
Xi-Lin OUYANG
Author Information
1. Department of Blood Transfusion, General Hospital of PLA, Center of Clinical Transfusion of PLA, Beijing 100853, China. Jinhan.liu@plagh.com.cn
- Publication Type:Journal Article
- MeSH:
Adenosine Triphosphate;
metabolism;
Antioxidants;
pharmacology;
Blood Preservation;
Erythrocytes;
drug effects;
physiology;
Humans;
Salvia miltiorrhiza
- From:
Journal of Experimental Hematology
2003;11(6):646-649
- CountryChina
- Language:Chinese
-
Abstract:
In order to optimize the preservation of blood, 3 kinds of antioxidant were selected and each of them can be injected directly into vein, then the optimal dose of these antioxidants was chosen using statistical method; ISMC (injectio salvia miltiorrhizae composita), ginaton and the combination of ISMC and ginaton were added into blood as optimal dose, some references as ATP, EI and so on were observed during blood preservation. The results showed that all of the three kinds of antioxidants increased ATP, EI and decreased FHb during blood preservation. It is concluded that both of ISMC and ginaton can effectively optimize the preservation of blood and combination of ISMC and ginaton can produce additive effect.
