Report on difficulty in blood group identification due to anti-H antibody in three cases.
- Author:
Rui-Qing XIAO
1
;
Wu-Cun LIN
;
Jia LIU
;
Tian-Lun JIANG
;
Han-Mei CHEN
;
Jie ZENG
;
Shu-Ming ZHAO
Author Information
1. Department of Blood Transfusion, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China.
- Publication Type:Journal Article
- MeSH:
ABO Blood-Group System;
immunology;
Adult;
Blood Grouping and Crossmatching;
Female;
Humans;
Isoantibodies;
blood;
Male;
Middle Aged
- From:
Journal of Experimental Hematology
2004;12(1):101-102
- CountryChina
- Language:Chinese
-
Abstract:
Anti-H antibody belongs to IgM type cold antibody, which often induces the unconformity of positive and reverse typing and leads to the difficulty in clinical blood typing. Anti-H antibody was found during identification of the counter blood group in 3 cases. The antibody was found to be active at 37 degrees C, room temperature and 4 degrees C when determined by blood group serology, and was finally analyzed to be IgM. It is suggested that not to give erythrocytes of O group unreasoningly to blood recipient of AB group during emergent moment, but instead, to give same type of blood. If there was no same type of blood during urgent events, O type erythrocytes could be employed after being matched by saline centrifuging with host side coincidence and screened by incomplete method. In this case, anti-H antibody leading to adverse-reaction in blood transfusion should be prevented.
