Research Advance on Role of Umbilical Cord Mesenchymal Stem Cell in Hematopoietic Stem Cells Transplantation-Review.

VernacularTitle:脐带间充质干细胞在造血干细胞移植中作用的研究进展
Author: Shu-Min QIAO ¹ ; Yi WANG ² ; Xiu-Ling SONG ¹ ; Yi-Nan YUE ¹
Author Information

1. Department of Pediatrics, The First People's Hospital of Jining, Jining 272000, Shandong Province, China.
2. Department of Hematology, Affiliated Children's Hospital of Soochow University, Suzhou 215003, Jiangsu Province, China. E-mail:wangdoctor@yahoo.cn.
Publication Type:Journal Article
From: Journal of Experimental Hematology 2017;25(6):1847-1850
CountryChina
Language:Chinese
Abstract: Hematopoietic stem cell transplantation is an important method for the treatment of hematological malignancies. The hematopoietic recovery after transplantation, graft-versus-host disease (GVHD) prevention and treatment are the key to affect transplant success. Umbilical cord mesenchymal stem cells (hUC-MSC) can improve the hematopoietic microenvironment, promote hematopoietic stem cell homing and hematopoietic recovery, support hematopoiesis. In aduition, the hUC-MSC have immune function for a variety of immune cells, can avoid and alleviate the host immune response, have a certain effect on the treatment of GVHD. This article reviews the research advances on umbilical cord mesenchymal stem cells in hematopoietic stem cell transplantation.