A Case of Gastric Outlet Obstruction Complicated by Peptic Ulcer Secondary to Non-Steroidal Anti-Inflammatory Drug (NSAID).
- Author:
Chang Hwan CHOI
1
;
Sung Hwan BYUN
;
Soo Hee CHANG
;
So Ya PAIK
Author Information
1. Department of Pediatrics, Bundang Jesaeng General Hospital, Seongnam, Korea. babydr@chol.com
- Publication Type:Case Report
- Keywords:
Peptic ulcer;
NSAID;
Gastric outlet obstruction
- MeSH:
Anti-Inflammatory Agents, Non-Steroidal;
Child;
Cyclooxygenase 1;
Dipyrone;
Fever;
Gastric Outlet Obstruction*;
Hemorrhage;
Humans;
Infant;
Peptic Ulcer*;
Seizures;
Ulcer
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2005;8(2):226-232
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Peptic ulcer disease complicated with gastric outlet obstruction is rare in children. Even though NSAIDs have been reported to cause various adverse events, they are still regarded as safe and, therefore, widely utilized in children. In the past, pediatric patients who were at risk of seizure due to high fever, were treated with dipyrone (Metamizole sodium) injection which inhibits cyclooxygenase-1 and inhibit prostaglandin, to weaken the gastro-duodenal defensive mechanism. A case of an infant with multiple esophagogatroduodenal ulcers and bleeding caused by NSAID complicated with gastric outlet obstruction is reported in this paper.