Small interfering RNA mediated multi-target therapy of cancer.
- Author:
Rong-guang SHAO
1
Author Information
1. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. shaor@public3.bta.net.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Genetic Therapy;
Humans;
Neoplasms;
genetics;
therapy;
RNA Interference;
RNA, Small Interfering;
genetics;
therapeutic use;
Radiation Tolerance
- From:
Acta Pharmaceutica Sinica
2009;44(3):219-225
- CountryChina
- Language:Chinese
-
Abstract:
It has been reviewed that as many as hundreds genes are dysregulated in various kinds of cancers, yet most therapies are targeted toward a single gene. Recently, the mode of cancer treatment has been changed by a shift in thinking from mono-target to multi-target therapies. There is considerable evidence that these have a higher possibility of success than mono-target therapy, and multi-target therapy should remain the most attractive avenue for future treatment strategies. In this article, we attempt to provide evidence for the role of small interfering RNA in multi-target therapy of cancer.
