The multi-target drugs and their design.
- Author:
Feng-chao JIANG
1
Author Information
1. School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, China. fengchao@mails.tjmu.edu.cn
- Publication Type:Journal Article
- MeSH:
Computer-Aided Design;
Drug Combinations;
Drug Delivery Systems;
methods;
Drug Design;
Humans;
Signal Transduction;
drug effects
- From:
Acta Pharmaceutica Sinica
2009;44(3):282-287
- CountryChina
- Language:Chinese
-
Abstract:
The reduce of bioactivity and augment of the side effect of single-target drugs is generated by the multi-factorial properties of the pathogenesis of disease, which could be solved by the multi-target drugs. The problems and its solution of the design of the multi-target drugs were discussed in this paper, at the same time, the design of the multi-target drugs by pharmacophore model method is presented.
