Apigenin glycosides from Euphorbia humifusa wild.
- Author:
Ying TIAN
1
;
Xi-qiao LIU
;
Jun-xing DONG
Author Information
1. Department of Pharmaceutical Chemistry, Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China.
- Publication Type:Journal Article
- MeSH:
Antiviral Agents;
chemistry;
isolation & purification;
pharmacology;
Apigenin;
chemistry;
isolation & purification;
pharmacology;
Cell Survival;
drug effects;
Euphorbia;
chemistry;
Glucosides;
chemistry;
isolation & purification;
pharmacology;
Glycosides;
Hep G2 Cells;
Hepatitis B Surface Antigens;
metabolism;
Hepatitis B e Antigens;
metabolism;
Humans;
Molecular Structure;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2009;44(5):496-499
- CountryChina
- Language:Chinese
-
Abstract:
The investigation on the herbal of Euphorbia humifusa Wild. was carried out in order to find its anti-HBV constituents. The isolation and purification were performed by chromatography such as Sephadex LH-20, MCI GEL CHP 20P, etc. Based on the spectral analysis, five apigenin glycosides were identified as apigenin-7-O-(6"-O-galloyl)-beta-D-glucopyranoside (1), apigenin-7-O-beta-D-apiofuranosyl (1-->2)-beta-D-glucopyranoside (2), apigenin-7-O-beta-D-lutinoside (3), apigenin-7-O-beta-D-glucopyranside (4) and apigenin (5). Among them, compound 1 is a new compound, compound 2 and 3 were isolated from this plant for the first time.
