Comparative study of pulmonary function after conventional ultrafiltration or modified ultrafiltration during cardiac surgery of infants.
- Author:
Jin-ping LIU
1
;
Cun LONG
;
Zheng-yi FENG
;
Bing-yang JI
;
Chun-hua LI
Author Information
- Publication Type:Clinical Trial
- MeSH: Cardiopulmonary Bypass; Female; Heart Defects, Congenital; physiopathology; surgery; Humans; Infant; Lung; physiopathology; Male; Respiratory Function Tests; Ultrafiltration; methods
- From: Acta Academiae Medicinae Sinicae 2002;24(4):364-366
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the effects of conventional ultrafiltration and modified ultrafiltration in protecting patients' pulmonary function during cardiopulmonary bypass.
METHODSThirty infants patients (less than 7 kg) were divided into two groups: conventional ultrafiltration group (CUF, n = 15) and modified ultrafiltration group (MUF, n = 15). The volume of ultrafiltration, transfusion, hematocrit (HCT) before and after ultrafiltration, patients' respiration function (respiration index, A-aDO2, airway pressure), the time of mechanical ventilation and ICU in the two groups were respectively monitored.
RESULTSThe transfusion in MUF group was significantly less than in CUF group (P < 0.01), and the volume of ultrafiltration in MUF group was significantly more than in CUF group (P < 0.01). The time of mechanical ventilation and ICU staying in MUF group were significantly shorter in MUF group than that in CUF group (P < 0.05). At 12 and 24 hours after operations, the A-aDO2 in MUF group was lower than that in CUF group (P < 0.05), and the respiratory index in MUF group was higher than that in CUF group (P < 0.05).
CONCLUSIONThe modified ultrafiltration can effectively improve pulmonary function after operations for low weight infants.
