Relationship of changes in sleep architecture and cognitive function in patients with obstructive sleep apnea syndrome.
- Author:
Yan XU
1
;
Shun-wei LI
;
Xi-zhen HUANG
;
Bo CONG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Cognition Disorders; etiology; Humans; Male; Middle Aged; Polysomnography; REM Sleep Behavior Disorder; etiology; Sleep Apnea, Obstructive; complications; psychology; Sleep Stages; physiology; Sleep, REM
- From: Acta Academiae Medicinae Sinicae 2002;24(6):632-634
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo explore the relationship between sleep architecture changes and cognitive impairment in patients with obstructive sleep apnea syndrome (OSAS).
METHODSThirty-six patients with OSAS and 18 controls were administered polysomnography and neuropsychological tests of visual regeneration, digital symbol, comprehensive memory and digital span.
RESULTSPerformances on the visual regeneration test and digital symbol test in patients with OSAS were impaired significantly compared with the control group (P < 0.01). Patients' performance on the visual regeneration test was significantly associated with slow wave sleep duration (r = 0.423, P < 0.05) and that on the digital symbol test was significantly associated with REM sleep duration (r = 0.378, P < 0.05).
CONCLUSIONSSlow wave sleep and REM sleep derivation may play a role in the cognitive impairment in patients with OSAS.
