A Case of Unilateral Renal Artery Stenosis with Contra-Lateral Focal Segmental Glomerulosclerosis in a Chronic Kidney Disease Patient.
- Author:
Sung Jin HONG
1
;
Dong Ki KIM
;
Cheol Ryong KU
;
Han Sung LEE
;
Kyu Hun CHOI
;
Ho Yung LEE
;
Dae Suk HAN
;
Hyeon Joo JEONG
;
Beom Seok KIM
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. docbsk@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Focal glomerulosclerosis;
Malignant hypertension;
Renal insufficiency;
Renal artery obstruction
- MeSH:
Adult;
Angiography;
Biopsy;
Blood Pressure;
Constriction, Pathologic;
Female;
Glomerulosclerosis, Focal Segmental*;
Humans;
Hypertension, Malignant;
Hypertension, Renovascular;
Kidney;
Kidney Failure, Chronic;
Proteinuria;
Receptors, Angiotensin;
Renal Artery Obstruction*;
Renal Artery*;
Renal Insufficiency;
Renal Insufficiency, Chronic*
- From:Korean Journal of Nephrology
2007;26(2):264-268
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of focal segmental glomerulosclerosis (FSGS) with chronic renal failure in a patient with unilateral renal artery stenosis. A 38-year-old woman presented with malignant hypertension, massive proteinuria and renal insufficiency. MR angiography showed proximal stenosis of the right renal artery and biopsy of the left kidney revealed focal segmental glomerulosclerosis. The patient responded favorably to the angiotensin II receptor antagonist, as the blood pressure and urinary protein decreased. This case showed that FSGS is a pathophysiologic mechanism of renal injury in uncontrolled renovascular hypertension.
