Advances in Evaluation of Cognitive Impairment in Patients with Cushing's Disease.
10.3881/j.issn.1000-503X.2016.06.019
- VernacularTitle:库欣病患者认知障碍的研究进展
- Author:
Wei-Yu MAO
1
;
Hui YOU
1
;
Bing XING
2
;
Hui-Juan ZHU
3
;
Feng FENG
1
Author Information
1. Department of Radiology, PUMC Hospital, CAMS and PUMC,Beijing 100730,China.
2. 2Department of Neurosurgery, PUMC Hospital, CAMS and PUMC,Beijing 100730,China.
3. Department of Endocrinology,PUMC Hospital, CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- MeSH:
Adenoma;
complications;
Cognition;
Cognitive Dysfunction;
complications;
diagnosis;
Cushing Syndrome;
complications;
Humans;
Hyperplasia;
Magnetic Resonance Imaging;
Pituitary ACTH Hypersecretion;
Pituitary Neoplasms;
complications
- From:
Acta Academiae Medicinae Sinicae
2016;38(6):735-738
- CountryChina
- Language:English
-
Abstract:
Cushing's disease (CD) is a relatively rare disease,characterized by pathological hypercortisolism secondary to excessive adrenocorticotrophic hormone that is secreted by pituitary adrenocorticotrophic hormone adenoma or hyperplasia. In addition to the typical clinical symptoms such as moon face,buffalo hump,and central obesity,the CD patients may also experience mental disorders and cognitive dysfunction. This review mainly focuses on the cognitive state of CD patients,the mechanisms of cognitive impairment caused by high cortisol levels,and the imaging findings (especially magnetic resonance imaging) for the evaluation of cognitive functions.
