C21 steroids from the stems of Marsdenia tenacissima.
- Author:
Yong-Sheng LEI
1
;
Zhan-Lin LI
;
Shen-Shen YANG
;
Zhi-Lan LIU
;
Hui-Ming HUA
Author Information
1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
- Publication Type:Journal Article
- MeSH:
Marsdenia;
chemistry;
Molecular Structure;
Plant Stems;
chemistry;
Plants, Medicinal;
chemistry;
Saponins;
chemistry;
isolation & purification;
Steroids;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2008;43(5):509-512
- CountryChina
- Language:Chinese
-
Abstract:
To study the C21 steroids of the stems of Marsdenia tenacissima (Roxb.) Wight et Arn, various chromatography methods were used for the isolation of the constituents and their structures were identified by spectral analysis. Eight C21 steroids were isolated from the CHCl3 extract, which were identified as 11alpha-O-tigloyl-17beta-tenacigenin B (1), 17beta-tenacigenin B (2), tenacigenoside A (3), 11alpha-O-2-methylbutyryl-12beta-O-acetyl tenacigenin B (4), tenacissoside H (5), marsdenoside A (6), tenacissoside G (7), and tenacissoside I (8). Among them, compound 1 is a new compound.