Safety and epidemiological effects of the first China-made mass A (H1N1) influenza vaccination

VernacularTitle:中国首批次甲型H1N1流感疫苗上市后安全性与保护效果的研究
Author: Wen-Yan JI ¹ ; Li LU ; Min LV ; Liang MIAO ; Ting GAO ; Ruo-Gang HUANG ; Luo-Dan SUO ; Dong-Lei LIU ; Rui MA ; Rui YU ; Jia-Zi ZHANGZHU ; Wei-Xiang LIU ; Yang ZENG ; Xiao-Mei LI ; Jiang WU
Author Information

1. 北京市疾病预防控制中心
Keywords: A (H1N1) influenza vaccine; Safety; Epidemiological effect
From: Chinese Journal of Epidemiology 2010;31(5):481-484
CountryChina
Language:Chinese
Abstract: Objective To evaluate the safety and epidemiological effects on the first mass vaccination program, using the China-made A (H1N1) influenza vaccine. Methods Descriptive epidemiology and cohort study design were used to assess the influenza A H1N1 vaccine on its safety and epidemiological effects. Results 95 244 subjects were immunized with A (H1N1) influenza vaccine. 193 adverse events were reported through AEFI Management System, with the Reported rates after immunization was carried out. Of 81 adverse reactions confirmed to be related to immunization,reported through the AEFI Management System. The epidemiological protection rate of A (H1N1)influenza vaccine showed a similar safety profile to seasonal flu vaccine. The vaccine demonstrated a good epidemiological effects against A (H1N1) influenza virus infection.