Serologic survey on pandemic influenza A (H1N1) virus among aged ≥3 years population from Jiangsu province in 2009, China
10.3760/cma.j.issn.0254-6450.2010.05.003
- VernacularTitle:江苏省2009年3岁以上自然人群新甲型H1N1流感血清流行病学调查
- Author:
Fen-Yang TANG
1
;
Rong-Qiang ZU
;
Liang LI
;
Xian QI
;
Hong JI
;
Bin WU
;
Ke XU
;
Jian-Guang FU
;
Yuan-Fang QIN
;
Fei DENG
;
Hai-Tao YANG
Author Information
1. 江苏省疾病预防控制中心
- Keywords:
Pandemic influenza A (H1N1) 2009;
Serologic survey;
Hemagglutination-inhibition assays;
Antibody
- From:
Chinese Journal of Epidemiology
2010;31(5):489-493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the antibody levels against pandemic influenza A (H1N1) virus (2009 H1N1 ) among aged ≥3 years population in 2009, from Jiangsu province, and to describe the distribution of 2009 H1N1. Methods Serum specimens were collected from natural populations at four different periods in Jiangsu, and tested with hernagglutination-inhibition (HI)assays. Rates of protective antibody against 2009 H1N1 and Geometric mean titers (GMTs)were estimated. Results The rates of protective antibody against 2009 H1N1 rose with the and November, 2009. There were no significant differences on the rates of protective antibody between males and females at four different cross-sectional periods (P＞0.05), and no significant differences on GMTs were observed at different periods except for November 2009. Significant differences on rates of protective antibody and GMTs among various age groups were observed at four different periods (P＜0.05), and similar results were observed among different periods in various age groups (P＜0.05). There were significant differences on rates of protective antibody and GMTs among different areas (P＜0.05). Conclusion The 2009 H1N1 strain had been widely spread out in Jiangsu province since July 2009. People aged 12-17 years became the major victims after August. As of November 2009, the rate of protective antibody against 2009 H1N1 was still low, predicting that the epidemic might continue to exist for a certain period of time.
