Study on the status of infection and distribution of rabies virus in China
10.3760/cma.j.issn.0254-6450.2010.05.011
- VernacularTitle:中国狂犬病毒感染分布状况调查
- Author:
Jin-Ning YU
1
;
Hao LI
;
Qing TANG
;
Xiao-Yan TAO
;
Hui WU
;
Zhao-Jun MO
;
Hong ZHANG
;
Ding-Ming WANG
;
Jing-Qing WENG
;
Rui-Hua SHEN
;
Feng-Cai ZHU
;
Xian-Jun WANG
;
Hong LIU
;
Xin-Xin SHEN
;
Shu-Mei WANG
Author Information
1. 中国疾病预防控制中心病毒病预防控制所
- Keywords:
Rabies;
Dogs;
Detection
- From:
Chinese Journal of Epidemiology
2010;31(5):521-524
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the status of infection and distribution of rabies virus (RV) in different epidemic areas in China. Methods Brain specimens from animals and suspected patients were collected at the districts of high-, medium- and low incidence rates of human rabies and detected by both direct Immunofluorescence assay (DFA) and RT-PCR. Results 254 of 3007 specimens of dog brains showed RV positive by DFA (positive rate of 8.4% ). Among these 254 samples, 78 showed positive (positive rate of 30.7% ) by RT-PCR. 93 specimens from dogs and cats that had attacked human beings, 63 of them showed positive by DFA (positive rate of 67.7%) and all of them were also positive by RT-PCR. In addition, RV could also be detected in Apodemus agrarius,ferret badger, and suspected patients specimens from the districts under survey. There was no statistical difference between the infection rates of RV in different provinces and regions with different incidence of rabies. Conclusion There might be a relatively high infection rate of RV among the domestic dogs/cats in the endemic areas in China. Wild animals might have been infected with RV in the districts under survey.
