A nested case-control study on the influencing factors of tuberculosis among people living with HIV/AIDS in Hunan province
10.3760/cma.j.issn.0254-6450.2010.02.008
- VernacularTitle:湖南省HIV/AIDS人群结核发病影响因素的巢式病例对照研究
- Author:
Meng-Shi CHEN
1
;
Hua-Lin YANG
;
Yon-Fang CHEN
;
Hong-Zhuan TAN
;
Li-Qiong BAI
;
Yan-Hui ZHANG
;
Jun LIU
;
Gui-Ping LI
Author Information
1. 中南大学
- Keywords:
Acquired immunedeficiency syndrome;
Tuberculosis;
Nested case-control study;
Influencing factors
- From:
Chinese Journal of Epidemiology
2010;31(2):151-154
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the risk factors related to tuberculosis infection among people living with HIV/AIDS and to develop strategies for preventing the co-infection.Methods A 1:2matched nested case-control study was carried out to analyze the influencing factors of tuberculosis among people living with HIV/AIDS.Results 1018 people living with HIV/AIDS were followed up for one year with a total number of 736.75 person-years,among them 62 tuberculosis cases were diagnosed.The incidence density of tuberculosis among people living with HIV/AIDS was 8.42 persons per 100 person-years.Factors as education level(OR=0.483),vaccination history of Bacille Calmette Guerin(OR=0.561),CD_4~+ count T-lymphocyte(OR=0.356),unemployment(OR=1.976),living alone(OR=2.646),and smoking(OR=2.215)were significantly related to the prevalence of tuberculosis among people living with HIV/AIDS.Conclusion High education level,with vaccination history of Bacille Calmette Guerin and high level of CD_4~+ T-lymphocyte count were protective factors while being unemployed,living alone,and smoking habit were risk factors related to the prevalence of tuberculosis among people living with HIV/AIDS.
