Hurthle cell thyroid tumor: an analysis of 28 cases
10.3760/cma.j.issn.1673-0860.2010.11.009
- VernacularTitle:甲状腺嗜酸细胞肿瘤28例诊治分析
- Author:
Xiao-Yong YANG
1
;
Chuan-Xiang HU
;
Li-Zhen YANG
;
Wen-Chuan ZHAO
;
Yi PAN
Author Information
1. 天津医科大学附属肿瘤医院
- Keywords:
Thyroid neoplasms;
Adenoma,oxyphilic;
Prognosis
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2010;45(11):908-911
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features and the combined treatment modality of Hurthle cell thyroid tumor(HCT). Methods Twenty-eight cases of HCT treated between 2001 and 2009were analyzed retrospectively. Results The age of the patients ranged from 18 to 72 years (with a median of 46.5 years); 22 females and 6 males. The main symptoms were thyroid solitary node or mass(22 cases)and multiple nodule(6 cases), 2 cases with cervical lymph node metastasis. All of the patients underwent surgery, 11 cases with thyroid lobectomy, 11 cases with thyroid lobectomy plus isthmusectomy, 4 cases with subtotal thyroidectomy, and 2 cases with thyroid lobectomy plus isthmusectomy and combined with modified radical cervical lymph node dissection. Postoperative pathological examination showed that 22 cases were Hurthle cell adenomas and 6 cases were Hurthle cell carcinomas, 1 of them with cervical lymph nodemetastasis. Twenty-one patients with Hurthle cell adenomas were followed up for 6 months to 7.5 years (with a median of 45 months) and 6 patients with Hurthle cell carcinomas for 3 to 8 years (with a median of 54 months), with no recurrence and death case. Conclusions HCT is a potential malignant neoplasm.There are some difficulties in the diagnosis of HCT by frozen section. Surgery is an effective treatment for HCT. L-Thyroxine can be used to inhibit TSH excretion.
