Complications of CO2 laser surgery in the treatment of laryngeal carcinoma
10.3760/cma.j.issn.1673-0860.2011.02.007
- VernacularTitle:CO2激光手术治疗喉癌的并发症分析
- Author:
Jiao-Jiao WU
1
;
Zhi-Gang HUANG
;
Ju-Gao FANG
;
Xue-Jun CHEN
;
Wei-Guo ZHOU
;
Zhen-Kun YU
;
Jun-Wei HUANG
Author Information
1. 首都医科大学附属北京同仁医院
- Keywords:
Laryngeal neoplasms;
Laser therapy;
Intraoperative complications;
Postoperative complications
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2011;46(2):118-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the complications of CO2 laser surgery in the treatment of laryngeal carcinoma,to analyze related factors and to propose preventive measures.Methods Retrospective analysis of 912 cases of laryngeal carcinoma(35 cases of supraglottic cancer and 877 cases of glottic cancer)treated only with laser surgery in Tongren Hospital was carried out.Among the glottic cancer,carcinoma in situ (Tis),T1,T2 and T3 were 53,659,158 and 7 cases.The follow-up period ranged from 2 to 18 years,with a median follow-up time of 9.3 years.Results Of 912 cases,824 cases were still alive,29 cases failed to be followed-up(taken into dead number),and 59 cases were dead.The recurrent rate was 9.4%(86/912).Three year survival rate was 95.6% (775/811)and five year survival rate was 87.9%(518/589).The incidence of surgery complications was 9.1% (83/912).Incidence of complications in supraglottic carcinoma and glottic carcinoma were 17.1% (6/35) and 8.8% (77/877),respectively,with no difference between the two groups (χ2 = 2.85,P ＞ 0.05).Incidence of complications of Tis,T1,T2 and T3 cases of glottic cancer were 5.7% (3/53),7.8% (51/659),13.3% (21/158) and 28.6% (2/7)respectively,with significant difference (χ2 = 8.97,P ＜ 0.05).Incidence of complications of glottic carcinoma with and without anterior commissure indision were 12.8% (31/242) and 7.2% (46/635)respectively,with significant difference between the two groups (χ2 = 6.78,P ＜ 0.05) .Incidence of complications in the patients underwent type Ⅱ ,Ⅲ,Ⅳ,Ⅴ cordectomy were 3.8% (4/105),7.0%(20/287),9.7% (22/226) and 12.0% (31/259) respectively,with significant difference (χ2 =7.96,P ＜0.05).Conclusions There are some potential risks and complications intra- and post-operatively,according to the sites and extent of the primary tumors and the range and depth of removed tissues.It needs to take active preventive measures to reduce the incidence of complications.
