Deep lingual arterial chemoembolization of tongue carcinoma with microcapsuled anticancer drug.
- Author:
Hong HE
1
;
Jian-qi HUANG
;
Fei-yun PING
;
Guan-fu CHEN
;
Su-zhan ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Antineoplastic Agents; administration & dosage; Capsules; Carboplatin; administration & dosage; Chemoembolization, Therapeutic; methods; Drug Carriers; administration & dosage; Humans; Injections, Intra-Arterial; Tongue; drug effects; Tongue Neoplasms; therapy
- From: Journal of Zhejiang University. Science. B 2007;8(10):704-708
- CountryChina
- Language:English
-
Abstract:
OBJECTIVEMicrocapsule chemoembolism is a promising treatment of tumors. We describe a deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum.
METHODSLingual artery cast specimens from cadavers were microscopically examined, and 78 patients with tongue cancer were recruited and treated with the deep lingual arterial embolization therapy.
RESULTSMicrocapsule embolism occurred approximately at the fifth or sixth level of the deep lingual artery branches. The five-year survival rate was 88.5% (69 out of 78), and the ten-year survival rate 52.6% (41 out of 78).
CONCLUSIONThe deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum is an effective therapy to treat carcinoma in mid-margin or mid-body of the tongue.
