WOMBAT: a tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML).
- Author:
Karin MEYER
1
Author Information
1. Animal Genetics and Breeding Unit, University of New England, Armidale, NSW, Australia. kmeyer@didgeridoo.une.edu.au
- Publication Type:Journal Article
- MeSH:
Animals;
Likelihood Functions;
Mice;
Models, Genetic;
Software
- From:
Journal of Zhejiang University. Science. B
2007;8(11):815-821
- CountryChina
- Language:English
-
Abstract:
WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable program, available for LINUX and WINDOWS environments, manual and a set of worked example, and can be downloaded free of charge from (http://agbu. une.edu.au/~kmeyer/wombat.html).
