- Author:
Zhi-hao XU
1
;
Chun-fu WANG
;
Yue-qin ZHANG
;
Hua-hao SHEN
;
Feng XU
Author Information
- Publication Type:Case Reports
- MeSH: Bacterial Vaccines; therapeutic use; Biological Products; therapeutic use; Chylothorax; drug therapy; pathology; Female; Humans; Middle Aged; Streptococcus; chemistry; Tomography, X-Ray Computed
- From: Journal of Zhejiang University. Science. B 2007;8(12):885-887
- CountryChina
- Language:English
- Abstract: Chylothorax is an uncommon disease where fatty fluid accumulates within the chest cavity. Conservative management, including repeated thoracentesis or pleurodesis, seems to be suitable to most cases. Herein, we present a case of efficacious pleurodesis by intrapleural injection of Sapylin, a streptococcus preparation, for the treatment of chylothorax. A 52-year-old non-smoking female farmer was diagnosed as idiopathic chylothorax after we ruled out possible causes including chest trauma, lymphoma, lung cancer, filariasis, tuberculosis, and etc. Two-time intra-thoracic injection of 3 Klinische Einheit (KE) Sapylin achieved rapid and effective control of chylothorax with no severe side effects. Sapylin may facilitate pleurodesis by producing a strong inflammatory response.