Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children.
- Author:
Yu-zhi CHEN
1
;
Yu MA
;
Hong-yu WANG
;
Hai-jun WANG
;
Jing ZHAO
;
Ling CAO
;
Shuo LI
;
G W K WONG
;
Nan-shan ZHONG
;
T F FOK
;
C K W LAI
Author Information
1. Capital Institute of Pediatrics, Beijing 100020 China.
- Publication Type:Journal Article
- MeSH:
Allergens;
classification;
immunology;
Asthma;
etiology;
immunology;
Bronchial Hyperreactivity;
etiology;
immunology;
Child;
China;
Hong Kong;
Humans;
Risk Factors;
Skin Tests;
Surveys and Questionnaires
- From:
Chinese Journal of Pediatrics
2003;41(7):538-541
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE This study aimed to determine the relationship between individual allergens with current wheezing and bronchial hyperresponsiveness (BHR) in schoolchildren from three chinese cities: Beijing, Guangzhou and Hong Kong. METHODS Community-based random samples of 10-yr-old schoolchildren from the 3 cities were recruited for study using the International Study of Asthma and Allergies in Childhood (ISAAC) Phase II protocol. The subjects were studied by parental questionnaires (n = 10,902), skin-prick tests (n = 3478), and methacholine challenge tests (n = 608). RESULTS The highest prevalence rates of wheezing in the past 12 months (Beijing, 3.8%; Guangzhou, 3.4%; Hong Kong, 5.8%) and atopy (Beijing, 23.9%; Guangzhou, 30.8%; Hong Kong, 41.2%, defined as having
