Studies on the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil extracted with CO2 supercritical fluid.
- Author:
Ai-jun ZHANG
1
;
Ning ZHU
;
An-dong YANG
Author Information
- Publication Type:Journal Article
- MeSH: Carbon Dioxide; Chromatography, Supercritical Fluid; Drug Carriers; Ligusticum; chemistry; Oils, Volatile; administration & dosage; isolation & purification; Plant Roots; chemistry; Plants, Medicinal; chemistry; Technology, Pharmaceutical; methods; Temperature; Time Factors; beta-Cyclodextrins
- From: China Journal of Chinese Materia Medica 2004;29(1):39-41
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil.
METHODOrthogonal test was used to evaluate the influence of the 4 factors, including the proportion of volatile oil to beta-cyclodextrin, the mode of mixing, inclusion temperature and mixing time.
RESULTThe best inclusion condition is the proportion of volatile oil to beta-cyclodextrin 1:9, the mode of mixing grinding, inclusion temperature 60 degrees C and inclusion time 90 min.
CONCLUSIONThe best inclusion technology of chuanxiong volatile oil is confirmed.
