Focal Liver Lesion Detection in Gadoxetic Acid-enhanced Liver MRI: Effects of Scan Delay, Hepatic Function, and Magnetic Field Strength.
10.13104/jksmrm.2011.15.3.226
- Author:
Hua Sun KIM
1
;
Myeong Jin KIM
;
Jae Joon CHUNG
;
Joon Suk LIM
;
Yong Eun CHUNG
;
Mi Suk PARK
;
Ki Whang KIM
Author Information
1. Department of Diagnostic Radiology and Institution of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea. kimnex@yuhs.ac
- Publication Type:Original Article
- Keywords:
Magnetic resonace imaging (MRI);
Liver;
Gadoxetic acid;
GD-EOB-DTPA
- MeSH:
Gadolinium DTPA;
Humans;
Liver;
Magnetic Fields;
Magnetic Resonance Spectroscopy;
Magnetics;
Magnets;
Retrospective Studies;
ROC Curve;
Sensitivity and Specificity
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2011;15(3):226-233
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To determine the effects of scan delay, hepatic function, and magnetic field strength on the performance of gadoxetic acid enhanced magnetic resonance imaging. MATERIALS AND METHODS: Gadoxetic acid enhanced MRI conducted in 72 patients with 10 minutes and 20 minutes delay were reviewed retrospectively. For quantitative analysis, liver-to-lesion signal difference ratio (SDR) was measured and compared according to scan delay time, hepatic function and magnetic field strength. For qualitative analysis, two board-certificated radiologists reviewed 10-minute delay and 20-minute delay images. The sensitivity and specificity of each reader was compared. RESULTS: The SDR of 20-minute images in non-cirrhotic patients was significantly higher (p < 0.01) than that of 10-minute delay images. However, in cirrhotic patients, it was comparable (p > 0.05) to 10-min delay images. In comparisons according to the magnetic strength, there was no significant difference between 1.5-T and 3.0-T systems. Comparisons of ROC curves showed no statistically significant differences in sensitivity and specificity between 10-minute and 20-minute delay images. CONCLUSION: An increase in the liver-to-lesion signal difference ratio was dependent on the patients' hepatic function but not dependent on the magnetic strength. There was no significant difference in sensitivity or specificity between the 10-minute and 20-minute delay images.
