Comparison of Non-invasive Imaging Studies in the Evaluation of Carotid Artery Stenosis and Occlusion: CT Angiography, Time-of-Flight MR Angiography and Contrast-Enhanced MR Angiography.
10.13104/jksmrm.2011.15.3.234
- Author:
Junhyung LEE
1
;
Tae Sub CHUNG
;
Kyung Yul LEE
;
Sang Hyun SUH
Author Information
1. Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Korea. suhsh11@yuhs.ac
- Publication Type:Original Article
- Keywords:
Carotid artery stenosis;
Computed tomography angiography (CTA);
Magnetic resonance angiography (MRA)
- MeSH:
Angiography;
Carotid Arteries;
Carotid Stenosis;
Constriction, Pathologic;
Humans;
Prospective Studies;
Sensitivity and Specificity;
Ultrasonography, Doppler, Color
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2011;15(3):234-241
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We compared non-invasive imaging studies of CTA, TOF-MRA and CE-MRA to evaluate detecting internal carotid artery stenosis and occlusion. MATERIALS AND METHODS: We enrolled 20 patients with clinically suspected internal carotid artery stenosis and occlusion, or asymptomatic patient with more than 50% stenosis suspected on color Doppler ultrasonography for regular check-up. Prospectively, CTA, TOF-MRA and CE-MRA were performed, and sensitivity, specificity, positive predictive value, negative predictive value and accuracy of TOF-MRA and CE-MRA using CTA as a reference standard for detecting more than 50% stenosis were evaluated, and correlations of measured percent stenosis between 3 imaging studies were also evaluated. RESULTS: No significant difference was found between 3 imaging studies in measuring stenosis(p>0.05). Correlation coefficient was 0.932 between CTA and TOF-MRA, and 0.971 between CTA and CE-MRA. TOF-MRA had 83.3% sensitivity, 87.5% specificity, 71.4% positive predictive value, 93.3% negative predictive value and 86.4% accuracy for detecting more than 50% stenosis and occlusion. CE-MRA had 83.3% sensitivity, 93.8% specificity, 83.3% positive predictive value, 93.8% negative predictive value and 90.9% accuracy. CONCLUSION: TOF-MRA and CE-MRA provided high correlations in the evaluation of internal carotid artery stenosis and occlusion.
