Studies on the active constituents in vine stem of Spatholobus suberectus.

Author: Yan-jun CUI ¹ ; Ping LIU ; Ruo-yun CHEN
Author Information

1. Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Bejing 100050 China.
Publication Type:Journal Article
MeSH: Animals; Catechin; analogs & derivatives; chemistry; isolation & purification; pharmacology; Cell Proliferation; drug effects; Fabaceae; chemistry; Gallic Acid; analogs & derivatives; chemistry; isolation & purification; Hematopoietic Stem Cells; cytology; Mice; Plant Stems; chemistry; Plants, Medicinal; chemistry; Vanillic Acid; chemistry; isolation & purification
From: China Journal of Chinese Materia Medica 2005;30(2):121-123
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the active constituents in vine stem of Spatholobus suberectus.
METHODThe constituents of Spatholobus suberectus were systematically separated with various chromatographic techniques. The structures were elucidated by physico-chemical properties and spectral data.
RESULTEight compounds were isolated from S. suberectus, and were identified as: ononin (1), pruneitin (2), gallocatechin (3), catechin (4), epicatechin (5), syringic acid (6), vanillic acid (7) and daucosterol (8).
CONCLUSIONCompound 3, 4, 6, 7 were obtained from Spatholobus genus for the first time. Compound 4 has stimulation to proliferation of hematopoietic progenitor cell.