Effects of processing Phellodendron amurense with salt on anti-gout.
- Author:
Cheng YANG
1
;
Ji-xiao ZHU
;
Yin WANG
;
Yao-lin WEN
;
Ling-dong KONG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Drugs, Chinese Herbal; isolation & purification; pharmacology; Gout Suppressants; pharmacology; Hot Temperature; Hyperuricemia; blood; enzymology; Liver; enzymology; Male; Mice; Phellodendron; chemistry; Plants, Medicinal; chemistry; Random Allocation; Sodium Chloride; Technology, Pharmaceutical; methods; Uric Acid; blood; Xanthine Oxidase; metabolism
- From: China Journal of Chinese Materia Medica 2005;30(2):145-148
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effects of processing Phellodendron anurene with salt on anti-gout.
METHODThe mouse serum uric acid level and liver xanthine oxidase activity were used to evaluate anti-gout effects of raw and processing P. amurense with salt.
RESULTBoth raw and processing P. amurense with salt reduced serum uric acid levels in the in hyperuricemic mice, and inhibited activities of liver xanthine oxidase at the low and high doses respectively, thus exhibiting anti-gout effects. Moreover, they showed the tendency to decrease the uric acid levels in the normal animal only at the high dose. The latter was a little weaker than the former.
CONCLUSIONProcessing with salt might not significantly change anti-gout effect of P. amurense.
