Progress in research on triptolide.
- Author:
Ming-xing LIU
1
;
Jing DONG
;
Ya-jiang YANG
;
Xiang-liang YANG
;
Hui-bi XU
Author Information
1. The Research Institute of Pharmaceutics, Huazhong University of Science and Technology, Wuhan 430074, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Anti-Inflammatory Agents, Non-Steroidal;
pharmacology;
Antineoplastic Agents, Alkylating;
pharmacology;
Antispermatogenic Agents;
pharmacology;
Diterpenes;
chemical synthesis;
isolation & purification;
pharmacology;
toxicity;
Epoxy Compounds;
Humans;
Immunosuppressive Agents;
pharmacology;
Phenanthrenes;
isolation & purification;
pharmacology;
toxicity;
Tripterygium;
chemistry
- From:
China Journal of Chinese Materia Medica
2005;30(3):170-174
- CountryChina
- Language:Chinese
-
Abstract:
To further understand triptolide, this paper has introduced the pharmacology, pharmacokinetics, toxicity, the clinic application and semi-synthesis of triptolide on basis of importance and significant contents of reference which have been consulted in the past twenty years. Presently triptolide and Tripterygium wilfordii have been a hot spot of modernization of Chinese traditional medicine. It is very important to develop a new dosage form of high effect and low toxicity by making use of advanced technology according to its characteristics.
