Studies on purification of the extract of fructus Gardeniae for injection by macroreticular resins.
- Author:
Gang CHEN
1
;
Shi-xiang HOU
;
Li-min YE
;
Ping HU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Drugs, Chinese Herbal; administration & dosage; isolation & purification; toxicity; Fruit; chemistry; Gardenia; chemistry; Injections; Iridoids; isolation & purification; Mice; Plants, Medicinal; chemistry; Pyrans; isolation & purification; Quality Control; Resins, Synthetic; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2005;30(3):188-190
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo purify the extract of fructus gardeniae for injection by macroreticular resins in purification process of traditional Chinese medicine (TCM) Injections.
METHODUsing fructus gardeniae as sample, on base of obtaining the extract by employing macroreticular resin, quality evaluation and rationality of purification methods had been studied by the quantitative analysis of active ingredients and the characteristics of micromeritics, safety and stability of the extract.
RESULTThe experiment showed the extract of fructus gardeniae for injection had been produced successfully by macroreticular resin.
CONCLUSIONUsing macroreticular resins is a promising purification way of TCM injections, whereas a more consummate method of quality evaluation must be established to ensure safety, efficiency and stability of the preparation in the process.
