Experimental study on pharmacodynamical of Oxalis griffithii, a national medicine in Guizhou.
- Author:
De-xun SONG
1
;
Jian-zhong DAI
;
Xue-yu ZHANG
;
Kai-yong ZHAO
;
Ming-qiang XU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Anti-Bacterial Agents; pharmacology; Anti-Inflammatory Agents, Non-Steroidal; pharmacology; Capillary Permeability; drug effects; Carrageenan; Drugs, Chinese Herbal; isolation & purification; pharmacology; Edema; chemically induced; drug therapy; Escherichia coli Infections; drug therapy; Female; Fever; drug therapy; Magnoliopsida; chemistry; Male; Mice; Mice, Inbred ICR; Phytotherapy; Plants, Medicinal; chemistry; Rats; Rats, Sprague-Dawley
- From: China Journal of Chinese Materia Medica 2005;30(3):215-218
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the on effects of anti-bacteria, anti-inflammatory and pyretolysis of Oxalis griffithii, it is possible safety.
METHODThe mice model was established by xylene (auricle smear method) and carrageenin (injection under the aponeuroses) respectively, rat febrile model was builded by 2,4-dintrophenol injection, and observe the effects of anti-bacteria in vitro that contracted by Staph aureus, Escherichia, Shigella, Pseudomonas, Aeruginosa. The mice model of experiment study on urgent poison effects (injection under the aponeuroses).
RESULTIt was found that the mouse ear edema induced by xylene, the increased vascular permeability caused by xylene were all significantly suppressed by Oxalis griffithii. At the same time, it could depressed the rat fervescence by 2,4-dinitrophenol. In addition, it has effect on fighting against Escherichia coli in cavum abdominis of mice. Oxalis griffithii hasn't canker affect.
CONCLUSIONThese results suggested that Oxalis griffithii had the effects of antinflammatory, pyretolysis, and safety.
