Study on chromatogrqphic fingerprint of qingying injection.
- Author:
Wen-yu FENG
1
;
Hua-rong QIU
;
Ji TIAN
;
Jun DU
;
Bing HE
Author Information
- Publication Type:Journal Article
- MeSH: Artemisia annua; chemistry; Chromatography, Gas; Chromatography, High Pressure Liquid; methods; Drug Combinations; Drugs, Chinese Herbal; administration & dosage; chemistry; isolation & purification; Injections; Lonicera; chemistry; Quality Control
- From: China Journal of Chinese Materia Medica 2004;29(2):141-146
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo establish the fingerprint detecting standard of Qingyin injection.
METHODBy adopting GC and HPLC, camphor and chlorogenic acid were used as reference material. To analyze separately Qingyin injection which contains volatile and non-volatile chemials. According to the technical requirements of fingerprint on Injection of Chinese traditional medicine, we calculated their bn relative retention time and area proportionality of peaks to determine the common peaks of fingerprint.
RESULTOn the basis of systematic methodalogy, we tested and analyzed 13 batches of sample injection so as to establish GC and HPLC fingerprint of the injection.
CONCLUSION15 common peaks on GC and 6 common peaks as well as their retention time and area proportionality on HPLC can be used as the important parameters of the quality control for Qingyin injection.