Clinical analysis of 60 cases with maxillary squamous cell carcinoma.
- Author:
Zai-xing ZHANG
1
;
Zheng-jiang LI
;
Zhen-gang XU
;
Ping-zhang TANG
;
Zong-min ZHANG
;
Chang-ming AN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; diagnosis; therapy; Combined Modality Therapy; Female; Humans; Lymphatic Metastasis; Male; Maxillary Sinus Neoplasms; diagnosis; therapy; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Young Adult
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(7):560-564
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the clinical characters, treatment modalities and prognosis of patients with maxillary squamous cell carcinoma.
METHODSThe clinical data of 60 patients with maxillary squamous cell carcinoma treatment between January 1994 and December 2004 were analyzed retrospectively. The patients were treated with three therapy modalities including radiotherapy alone (22 cases), radiotherapy and surgery (R + S, 29 cases) and concurrent chemo-radio-therapy adjuvant surgery (CCR + S, 9 cases).
RESULTSThe five year survival rate were 18.2%, 51.7% and 33.3% for patients in the radiotherapy alone group, the R + S group and the CCR + S group, respectively. Patients receiving R + S combined modality therapy had a significantly higher five year survival rate than the patients who were treated radiotherapy alone (χ(2) = 15.62, P < 0.01). The five year survival rate (51.7%) of patients in R + S group was significantly higher than that (33.3%) of patients in CCR + S group (χ(2) = 4.28, P < 0.05), and also higher than that (18.2%) of patients in radiotherapy group (χ(2) = 9.49, P < 0.01).
CONCLUSIONSThe combined therapy of radiation and surgery was a good choice of treatment for the patients with maxillary sinus squamous cell carcinoma. The role of concurrent chemo-radiotherapy adjuvant surgery in the treatment of maxillary sinus squamous cell carcinoma needs further to research.
