Correlation analysis of two serum specific IgE test systems and skin prick test in allergic rhinitis patients.
- Author:
Xiao-dan JIANG
1
;
Guang-yu LI
;
Ji-chao SHA
;
Xue-wei ZHU
;
Cui-da MENG
;
Zhen DONG
;
Dong-dong ZHU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Child; Female; Humans; Immunoglobulin E; blood; Male; Middle Aged; Rhinitis, Allergic, Perennial; blood; diagnosis; immunology; Sensitivity and Specificity; Skin Tests; Young Adult
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(8):652-655
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the correlation between two serum specific IgE and skin prick test (SPT) for the diagnosis of allergic rhinitis.
METHODSTwo hundred and sixteen patients were referred to the allergist for a suspected allergic rhinitis between June and October in 2009. Patients were classified as positive for inhalant allergy if they had a positive clinical history and a related positive SPT for the suspected inhalant allergen. Statistical analysis was performed using SPSS13.0 software.
RESULTSOne hundred and fifty-eight patients had a positive SPT, comparing with the SPT, the diagnostic indexes (accuracy, sensitivity, specificity) of the ImmunoCAP system and the AllergyScreen system were 0.810 and 0.819, 0.872 and 0.780, 0.741 and 0.862 respectively. The accuracy was similar between the two systems (χ(2) = 0.112, P > 0.05). The ImmunoCAP system had a higher sensitivity (χ(2) = 7.361, P < 0.05). The AllergyScreen system had a higher specificity (χ(2) = 10.222, P < 0.05).
CONCLUSIONSThis data supported the use of ImmunoCAP system and AllergyScreen system to identify potentially significant individual allergens in the diagnosis of allergic rhinitis. The ImmunoCAP system had a higher sensitivity. The AllergyScreen system had a higher specificity. The AllergyScreen system can be used as a complementary with the ImmunoCAP system.
