Preliminary study on the effects of an artificial liver support system in the treatment of medicamentous liver insufficiency.
- Author:
Jia SHANG
1
;
Yun XU
;
Yu-xiu YANG
;
Bai-ling JIA
;
He-ping ZHANG
;
Xiu JIN
;
Ping CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Antineoplastic Agents; adverse effects; Antitubercular Agents; adverse effects; Female; Hepatic Insufficiency; chemically induced; therapy; Humans; Liver, Artificial; Male; Middle Aged
- From: Chinese Journal of Hepatology 2005;13(11):836-838
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo study the effectiveness of an artificial liver support system.
METHODSThirty-two patients with medicamentous liver insufficiency were treated with an artificial liver support system in addition to the routine medicinal therapy. Thirty patients treated with routine medicinal therapy only served as controls.
RESULTSThe clinical symptoms (e.g. hepatic encephalopathy) and the laboratory indices (serum total bilirubin and prothrombin time) of the treatment group patients were obviously improved compared with those of the control group patients (P < 0.05). The cure rate and hospitalization days were 90.6% (26/32) and 47 days respectively in the treatment group, and 43.3% (13/30) and 72 days in the control group (P < 0.05).
CONCLUSIONUsing an artificial liver support system combined with routine medicinal therapy is more effective than using medication alone.