Research progresses of plant polysaccharides on cell adhesion.
- Author:
Xian-Xiang XU
1
;
Yong DIAO
;
Rui-An XU
;
Ai-Jing SUN
Author Information
1. Institute of Molecular Medicine, Huaqiao University, Quanzhou 362021, China. xuxianxiang@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Anti-Infective Agents;
isolation & purification;
pharmacology;
Anti-Inflammatory Agents;
isolation & purification;
pharmacology;
Antineoplastic Agents, Phytogenic;
isolation & purification;
pharmacology;
Cardiovascular Diseases;
pathology;
Cell Adhesion;
drug effects;
Humans;
Immunomodulation;
drug effects;
Infection;
pathology;
Inflammation;
pathology;
Neoplasms;
pathology;
Plants, Medicinal;
chemistry;
Polysaccharides;
isolation & purification;
pharmacology
- From:
Acta Pharmaceutica Sinica
2012;47(7):844-849
- CountryChina
- Language:Chinese
-
Abstract:
Cell adhesion mediated by cell adhesion molecules (CAMs) constitutes essential life phenomenon. In inflammation, immunity, infection, thrombosis, tumor metastasis and wound healing, cell adhesion comes into being the basic physiological and pathological process. Intervening with cell adhesion has been the important therapeutic and prophylactic strategies for diseases. Accumulated evidence has indicated that plant polysaccharides especially those exacted from Chinese traditional and herbal drugs displayed various pharmacological effects such as anti-inflammation, anti-cancer, anti-infection, immunomodulation, cardiovascular protective effects and so on. In this paper, the research progress of plant polysaccharides on cell adhesion is reviewed.
