Chemical constituents of Trichosanthes kirilowii Maxim.
- Author:
Xiao-Ye SUN
1
;
Hong-Hua WU
;
Ai-Zhen FU
;
Peng ZHANG
Author Information
1. Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Modern Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 300193, China.
- Publication Type:Journal Article
- MeSH:
Apigenin;
chemistry;
isolation & purification;
Flavones;
chemistry;
isolation & purification;
Fruit;
chemistry;
Glucuronates;
chemistry;
isolation & purification;
Molecular Structure;
Plants, Medicinal;
chemistry;
Pyrroles;
chemistry;
isolation & purification;
Trichosanthes;
chemistry;
Vanillic Acid;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2012;47(7):922-925
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents of Trichosanthes kirilowii Maxim., chromatographic methods such as D101 macroporous resin, silica gel column chromatographic technology, Sephadex LH-20, octadecylsilyl (ODS) column chromatographic technique and preparative HPLC were used and nine compounds were isolated from a 95% (v/v) ethanol extract of the plant. By using spectroscopic techniques including 1H NMR, 13C NMR, 1H-1H COSY, HSQC and HMBC, these compounds were identified as 5-ethoxymethyl-1-carboxyl propyl-1H-pyrrole-2-carbaldehyde (1), 5-hydroxymethyl-2-furfural (2), chrysoeriol (3), 4'-hydroxyscutellarin (4), vanillic acid (5), alpha-spinasterol (6), beta-D-glucopyranosyl-a-spinasterol (7), stigmast-7-en-3beta-ol (8), and adenosine (9), separately. Among them, compound 1 is a new compound, and compounds 3, 4 and 5 are isolated from the genus Trichosanthes kirilowii Maxim. for the first time.
