The research progress of preparation methods of solid nanocrystal delivery system.
- Author:
Peng-Fei YUE
1
;
Yong WANG
;
Jing WAN
;
Zhen-Feng WU
;
Peng-Yi HU
;
Qin ZHENG
;
Hai-Long YUAN
;
Ming YANG
Author Information
1. Key Lab of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. ypfpharm@126.com
- Publication Type:Journal Article
- MeSH:
Drug Delivery Systems;
Nanoparticles;
Nanotechnology;
methods;
Pharmaceutical Preparations;
administration & dosage;
chemistry
- From:
Acta Pharmaceutica Sinica
2012;47(9):1120-1127
- CountryChina
- Language:Chinese
-
Abstract:
Nanocrystal suspensions drug delivery system is used to solve the delivery difficulty of poorly soluble drug. However, the physical stability of liquid nanocrystal suspensions is very bad. Solid nanocrystal delivery system as a novel technology, can improve the thermokinetics stability of nanocrystal suspensions and have good clinical compliance, which can achieve stabilization of nanocrystal suspension systems as an ideal delivery system. In this paper, we reviewed the research progress of nanotechnology and solidification technology of solid nanocrystal suspension delivery system, which will give the new mirrors and thoughts on the development of solid nanocrystal delivery system.
